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  1. The aim of this study was to produce ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles (NPs) conjugated to the FROP-1 peptide for targeted magnetic resonance imaging (MRI) of breast cancer cell lin...

    Authors: Melika Samari, Zahra Alamzadeh, Rasoul Irajirad, Abolfazl Sarikhani, Vahid Pirhajati Mahabadi, Habib Ghaznavi and Samideh Khoei
    Citation: BMC Biomedical Engineering 2025 7:5
  2. COVID-19 has claimed the lives of thousands over the past years. Although pathogenic laboratory testing is the established standard, it carries a significant drawback with a notable rate of false negatives. Co...

    Authors: Rabih Assaf, Abbas Rammal, Alban Goupil, Mohammad Kacim and Valeriu Vrabie
    Citation: BMC Biomedical Engineering 2025 7:4
  3. Exposure to electric fields affects cell membranes impacting their potential and altering cellular excitability, nerve transmission, or muscle contraction. Furthermore, electric stimulation influences cell com...

    Authors: Jorge R. Cibrão, Miguel Armada, Marta F. Lima, André Vidinha-Mira, Jonas Campos, Tiffany S. Pinho, António J. Salgado, Alar Ainla and Nuna A. Silva
    Citation: BMC Biomedical Engineering 2025 7:3
  4. The ST response to high frequency EM heating may give an indication of rate of BF in underlying tissue. This novel method, which we have termed REFLO (Rapid Electromagnetic Flow) has potential for applications...

    Authors: Georgia E. H. Robles and David A. Nelson
    Citation: BMC Biomedical Engineering 2025 7:1
  5. Despite significant technological progress in prosthetic hands, a device with functionality akin to a biological extremity is far from realization. To better support the development of next-generation technolo...

    Authors: Joshua R. Siegel, Jedidiah K. Harwood, Annette C. Lau, Dylan J. A. Brenneis, Michael R. Dawson, Patrick M. Pilarski and Jonathon S. Schofield
    Citation: BMC Biomedical Engineering 2024 6:11
  6. This study introduces a novel surgical instrument to reduce iatrogenic nerve injuries during procedures such as carpal tunnel and ulnar nerve decompression surgery. These injuries often result from direct dama...

    Authors: Zach Spears, Molly Paras, Lauren Fitzsimmons, Logan De Lacy, Peter Wawrzyn, Sam Conway, Srihari Gopalan, Kyle Muckenhirn and John Puccinelli
    Citation: BMC Biomedical Engineering 2024 6:10
  7. Movement is a central behavior of daily living; thus lost or compromised movement due to disease, injury, or amputation causes enormous loss of productivity and quality of life. While prosthetics have evolved ...

    Authors: Sherif M. Elbasiouny
    Citation: BMC Biomedical Engineering 2024 6:9
  8. Restorative solutions designed for edentulous patients such as dentures and their accompanying denture adhesives operate in the complex and dynamic environment represented by human oral physiology. Developing ...

    Authors: Anantha Narayanan Ramakrishnan, Josephine Reymann, Christopher Ludtka, Andreas Kiesow and Stefan Schwan
    Citation: BMC Biomedical Engineering 2024 6:8
  9. This study is a pilot randomized clinical trial aimed to investigate the effect of using Hip Exoskeleton Assistive (HEXA) robot compared to conventional physiotherapy on the quality of walking, disability, and...

    Authors: Hamed Mamipour, Seyed Ali Hoseini, Hossein Negahban, Ali Moradi, Amir Hojjati, Fariborz Rezaeitalab, Mohammadreza Torshizian, Arefeh Mehrali, Mohammad Parsa, Iman Kardan, Hamed Tabesh, Ebrahim Ghayem Hassankhani and Alireza Akbarzadeh
    Citation: BMC Biomedical Engineering 2024 6:7
  10. Visualization of cancer during breast conserving surgery (BCS) remains challenging; the BCS reoperation rate is reported to be 20-70% of patients. An urgent clinical need exists for real-time intraoperative vi...

    Authors: Christopher Gibson, Shirley C. Wang, Arcturus Phoon, Nayana Thalanki Anantha, Kathryn Ottolino-Perry, Stephen Petropoulos, Zuha Qureshi, Vasanth Subramanian, Anam Shahid, Cristiana O’Brien, Steven Carcone, Suzanne Chung, Teresa Tsui, Viktor Son, Mayleen Sukhram, Fannong Meng…
    Citation: BMC Biomedical Engineering 2024 6:5
  11. Compared to classical techniques of morphological analysis, micro-CT (μ-CT) has become an effective approach allowing rapid screening of morphological changes. In the present work, we aimed to provide an optim...

    Authors: Azza Naïja, Onur Mutlu, Talha Khan, Thomas Daniel Seers and Huseyin C. Yalcin
    Citation: BMC Biomedical Engineering 2024 6:3
  12. MAR algorithms have not been productized in interventional imaging because they are too time-consuming. Application of a beam hardening filter can mitigate metal artifacts and doesn’t increase computational bu...

    Authors: Carlos A. Reynoso-Mejia, Jonathan Troville, Martin G. Wagner, Bernice Hoppel, Fred T. Lee Jr and Timothy P. Szczykutowicz
    Citation: BMC Biomedical Engineering 2024 6:2
  13. Infectious diseases not only cause severe health problems but also burden the healthcare system. Therefore, the effective treatment of those diseases is crucial. Both conventional approaches, such as antimicro...

    Authors: Basak Olcay, Gizem D. Ozdemir, Mehmet A. Ozdemir, Utku K. Ercan, Onan Guren and Ozan Karaman
    Citation: BMC Biomedical Engineering 2024 6:1
  14. A pressure ulcer (PU) is a debilitating condition that disproportionately affects people with impaired mobility. PUs facilitate tissue damage due to prolonged unrelieved pressure, degrading quality of life wit...

    Authors: Bethel Osuagwu, Euan McCaughey and Mariel Purcell
    Citation: BMC Biomedical Engineering 2023 5:8
  15. Epilepsy is a neurological disorder that has a variety of origins. It is caused by hyperexcitability and an imbalance between excitation and inhibition, which results in seizures. The World Health Organization...

    Authors: Mikael Habtamu, Keneni Tolosa, Kidus Abera, Lamesgin Demissie, Samrawit Samuel, Yeabsera Temesgen, Elbetel Taye Zewde and Ahmed Ali Dawud
    Citation: BMC Biomedical Engineering 2023 5:7
  16. In respiratory fluid dynamics research, it is typically assumed that the wall of the trachea is smooth. However, the trachea is structurally supported by a series of cartilaginous rings that create undulations...

    Authors: Humberto Bocanegra Evans, Jose Montoya Segnini, Ali Doosttalab, Joehassin Cordero and Luciano Castillo
    Citation: BMC Biomedical Engineering 2023 5:5
  17. Microelectrical Impedance Spectroscopy (µEIS) is a tiny device that utilizes fluid as a working medium in combination with biological cells to extract various electrical parameters. Dielectric parameters of bi...

    Authors: Sameh. Sherif, Yehya H. Ghallab, Omnia AbdelRaheem, Laila Ziko, Rania Siam and Yehea Ismail
    Citation: BMC Biomedical Engineering 2023 5:4
  18. The number of steps by an individual, has traditionally been assessed with a pedometer, but increasingly with an accelerometer. The ActiLife software (AL) is the most common way to process accelerometer data t...

    Authors: Ivar Holm, Jonatan Fridolfsson, Mats Börjesson and Daniel Arvidsson
    Citation: BMC Biomedical Engineering 2023 5:3
  19. This paper sets out to design a device for removing bubbles during the process of hemodialysis. The concept is to guide the bubbles while traveling through the device and eventually the bubbles can be collecte...

    Authors: Poonnapa Chaichudchaval, Nunthapat Fuangkamonvet, Supajitra Piboonlapudom and Teeranoot Chanthasopeephan
    Citation: BMC Biomedical Engineering 2023 5:2
  20. The ever-growing need for cheap, simple, fast, and accurate healthcare solutions spurred a lot of research activities which are aimed at the reliable deployment of artificial intelligence in the medical fields...

    Authors: Hafeez Alani Agboola and Jesuloluwa Emmanuel Zaccheus
    Citation: BMC Biomedical Engineering 2023 5:1
  21. Short-term emergency ventilation is most typically accomplished through bag valve mask (BVM) techniques. BVMs like the AMBU® bag are cost-effective and highly portable but are also highly prone to user error, esp...

    Authors: Benjamin S. Maxey, Luke A. White, Giovanni F. Solitro, Steven A. Conrad and J. Steven Alexander
    Citation: BMC Biomedical Engineering 2022 4:9
  22. Neural interface devices interact with the central nervous system (CNS) to substitute for some sort of functional deficit and improve quality of life for persons with disabilities. Design of safe, biocompatibl...

    Authors: Christopher T. Tsui, Preet Lal, Katelyn V. R. Fox, Matthew A. Churchward and Kathryn G. Todd
    Citation: BMC Biomedical Engineering 2022 4:7
  23. Replicating the mechanical behavior of human bones, especially cancellous bone tissue, is challenging. Typically, conventional bone models primarily consist of polyurethane foam surrounded by a solid shell. Al...

    Authors: F. Metzner, C. Neupetsch, A. Carabello, M. Pietsch, T. Wendler and W.-G. Drossel
    Citation: BMC Biomedical Engineering 2022 4:6
  24. Gluten, a food allergen, is available in foods derived from wheat, rye and barley. It damages the small intestine and causes celiac disease. Herein, we designed a rapid immunochromatographic lateral flow test ...

    Authors: Arefe Momeni, Mohammad Rostami-Nejad, Reza Salarian, Mohammad Rabiee, Elham Aghamohammadi, Mohammad Reza Zali, Navid Rabiee, Franklin R. Tay and Pooyan Makvandi
    Citation: BMC Biomedical Engineering 2022 4:5
  25. For brain tumors, identifying the molecular subtypes from magnetic resonance imaging (MRI) is desirable, but remains a challenging task. Recent machine learning and deep learning (DL) approaches may help the c...

    Authors: Muhaddisa Barat Ali, Irene Yu-Hua Gu, Alice Lidemar, Mitchel S. Berger, Georg Widhalm and Asgeir Store Jakola
    Citation: BMC Biomedical Engineering 2022 4:4
  26. The COVID-19 pandemic revealed a substantial and unmet need for low-cost, easily accessible mechanical ventilation strategies for use in medical resource-challenged areas. Internationally, several groups devel...

    Authors: Luke A. White, Benjamin S. Maxey, Giovanni F. Solitro, Hidehiro Takei, Steven A. Conrad and J. Steven Alexander
    Citation: BMC Biomedical Engineering 2022 4:2
  27. Detection of locally increased blood concentration and perfusion is critical for assessment of functional cortical activity as well as diagnosis of conditions such as intracerebral hemorrhage (ICH). Current pa...

    Authors: Shane Shahrestani, Gabriel Zada and Yu-Chong Tai
    Citation: BMC Biomedical Engineering 2022 4:1
  28. Controlled static exertion performed in the sagittal plane on a transducer attached to the foot requires coordinated moments of force of the lower extremity. Some exertions and plantarflexion recruit muscular ...

    Authors: Daniel Bourbonnais, René Pelletier, Joëlle Azar, Camille Sille and Michel Goyette
    Citation: BMC Biomedical Engineering 2021 3:12
  29. Automating cytology-based cervical cancer screening could alleviate the shortage of skilled pathologists in developing countries. Up until now, computer vision experts have attempted numerous semi and fully au...

    Authors: Mohammed Aliy Mohammed, Fetulhak Abdurahman and Yodit Abebe Ayalew
    Citation: BMC Biomedical Engineering 2021 3:11
  30. In response to supply shortages caused by the COVID-19 pandemic, N95 filtering facepiece respirators (FFRs or “masks”), which are typically single-use devices in healthcare settings, are routinely being used f...

    Authors: Malia McAvoy, Ai-Tram N. Bui, Christopher Hansen, Deborah Plana, Jordan T. Said, Zizi Yu, Helen Yang, Jacob Freake, Christopher Van, David Krikorian, Avilash Cramer, Leanne Smith, Liwei Jiang, Karen J. Lee, Sara J. Li, Brandon Beller…
    Citation: BMC Biomedical Engineering 2021 3:10
  31. Development of automatic, pneumatic tourniquet technology and use of personalised tourniquet pressures has improved the safety and accuracy of surgical tourniquet systems. Personalisation of tourniquet pressur...

    Authors: Luke Hughes and James McEwen
    Citation: BMC Biomedical Engineering 2021 3:8
  32. Glioblastoma Multiforme, an aggressive primary brain tumor, has a poor prognosis and no effective standard of care treatments. Most patients undergoing radiotherapy, along with Temozolomide chemotherapy, devel...

    Authors: Radhika Saraf, Shaghayegh Agah, Aniruddha Datta and Xiaoqian Jiang
    Citation: BMC Biomedical Engineering 2021 3:7
  33. Organoids are a reliable model used in the study of human brain development and under pathological conditions. However, current methods for brain organoid culture generate tissues that range from 0.5 to 2 mm o...

    Authors: Mariana Oksdath Mansilla, Camilo Salazar-Hernandez, Sally L. Perrin, Kaitlin G. Scheer, Gökhan Cildir, John Toubia, Kristyna Sedivakova, Melinda N. Tea, Sakthi Lenin, Elise Ponthier, Erica C. F. Yeo, Vinay Tergaonkar, Santosh Poonnoose, Rebecca J. Ormsby, Stuart M. Pitson, Michael P. Brown…
    Citation: BMC Biomedical Engineering 2021 3:6
  34. End-stage heart failure is a major risk of mortality. The conductive super-aligned carbon nanotubes sheets (SA-CNTs) has been applied to restore the structure and function of injured myocardium through tissue ...

    Authors: Quanfu Xu, Yuli Yang, Jianwen Hou, Taizhong Chen, Yudong Fei, Qian Wang, Qing Zhou, Wei Li, Jing Ren and Yi-Gang Li
    Citation: BMC Biomedical Engineering 2021 3:5
  35. Liver cancer is the sixth most common cancer worldwide. It is mostly diagnosed with a computed tomography scan. Nowadays deep learning methods have been used for the segmentation of the liver and its tumor fro...

    Authors: Yodit Abebe Ayalew, Kinde Anlay Fante and Mohammed Aliy Mohammed
    Citation: BMC Biomedical Engineering 2021 3:4
  36. Magnetic Resonance Imaging (MRI), a non-invasive method for the diagnosis of diverse health conditions has experienced growing popularity over other imaging modalities like ultrasound and Computer Tomography. ...

    Authors: Faith Natukunda, Theodora M. Twongyirwe, Steven J. Schiff and Johnes Obungoloch
    Citation: BMC Biomedical Engineering 2021 3:3
  37. Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric fi...

    Authors: Christina N. M. Ryan, Meletios N. Doulgkeroglou and Dimitrios I. Zeugolis
    Citation: BMC Biomedical Engineering 2021 3:1
  38. Bismuth compounds are known for their activity against multiple microorganisms; yet, the antibiotic properties of bismuth nanoparticles (BiNPs) remain poorly explored. The objective of this work is to further ...

    Authors: Roberto Vazquez-Munoz, M. Josefina Arellano-Jimenez and Jose L. Lopez-Ribot
    Citation: BMC Biomedical Engineering 2020 2:11
  39. A major challenge for any glaucoma implant is their ability to provide long-term intraocular pressure lowering efficacy. The formation of a low-permeability fibrous capsule around the device often leads to obs...

    Authors: Ian Grierson, Don Minckler, Marian K. Rippy, Andrew J. Marshall, Nathalie Collignon, Jessica Bianco, Benoit Detry and Murray A. Johnstone
    Citation: BMC Biomedical Engineering 2020 2:10
  40. High occupational physical activity is associated with lower health. Shoe-based movement sensors can provide an objective measurement of occupational physical activity in a lab setting but the performance of s...

    Authors: Jonatan Fridolfsson, Daniel Arvidsson, Frithjof Doerks, Theresa J. Kreidler and Stefan Grau
    Citation: BMC Biomedical Engineering 2020 2:8
  41. Tourniquets in orthopaedic surgery safely provide blood free surgical fields, but their use is not without risk. Tourniquets can result in temporary or permanent injury to underlying nerves, muscles, blood ves...

    Authors: Bassam A. Masri, Andrew Eisen, Clive P. Duncan and James A. McEwen
    Citation: BMC Biomedical Engineering 2020 2:7

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