Fig. 1

Neural control of movement under healthy conditions. Motor intent originates in the motor cortex and is transferred – via motor nerves and pathways – to activate spinal motoneurons in lamina IX of the ventral horn to eventually activate muscles. Generated movement activates sensory receptors in the periphery to send sensory information – via sensory nerves – back to spinal motoneurons and the sensory cortex, which evokes the sensation of touch